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Czech Republic

2020 Impact Factor Journals


Dvoranova J, Kugler M, Holub J, Sicha V, Das V, Nekvinda J, et al. Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX. European Journal of Medicinal Chemistry. 2020;200. ISSN 0223-5234. DOI: 10.1016/j.ejmech.2020.112460

Dzubak P, Gurska S, Bogdanova K, Uhrikova D, Kanjakova N, Combet S, et al. Antimicrobial and cytotoxic activity of (thio)alkyl hexopyranosides, nonionic glycolipid mimetics. Carbohydrate Research. 2020;488. ISSN 0008-6215. DOI: 10.1016/j.carres.2019.107905

Fleuti M, Bartova K, Slavetinska LP, Tloust'ova E, Tichy M, Gurska S, et al. Synthesis and Biological Profiling of Pyrazolo-Fused 7-Deazapurine Nucleosides. Journal of Organic Chemistry. 2020;85(16):10539-51. ISSN 0022-3263. DOI: 10.1021/acs.joc.0c00928

Garic D, De Sanctis JB, Dumut DC, Shah J, Pena MJ, Youssef M, et al. Fenretinide favorably affects mucins (MUC5AC/MUC5B) and fatty acid imbalance in a manner mimicking CFTR-induced correction. Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids. 2020;1865(2). ISSN 1388-1981. DOI: 10.1016/j.bbalip.2019.158538

Garic D, Dumut DC, Shah JH, De Sanctis JB, Radzioch D. The role of essential fatty acids in cystic fibrosis and normalizing effect of fenretinide. Cellular and Molecular Life Sciences. 2020;77(21):4255-67. ISSN 1420-682X. DOI: 10.1007/s00018-020-03530-x

Novy Z, Lobaz V, Vlk M, Kozempel J, Stepanek P, Popper M, et al. Head-To-Head Comparison of Biological Behavior of Biocompatible Polymers Poly(Ethylene Oxide), Poly(2-Ethyl-2-Oxazoline) and Poly N-(2-Hydroxypropyl)Methacrylamide as Coating Materials for Hydroxyapatite Nanoparticles in Animal Solid Tumor Model. Nanomaterials. 2020;10(9). ISSN 2079-4991. DOI: 10.3390/nano10091690

Veselovska L, Kudlova N, Gurska S, Liskova B, Medvedikova M, Hodek O, et al. Synthesis and Cytotoxic and Antiviral Activity Profiling of All-Four Isomeric Series of Pyrido-Fused 7-Deazapurine Ribonucleosides. Chemistry-a European Journal. 2020;26(57):13002-15. ISSN 0947-6539. DOI: 10.1002/chem.202001124

Yang C, Pohl R, Tichy M, Gurska S, Pavlis P, Dzubak P, et al. Synthesis, Photophysical Properties, and Biological Profiling of Benzothieno-Fused 7-Deazapurine Ribonucleosides. Journal of Organic Chemistry. 2020;85(12):8085-101. ISSN 0022-3263. DOI: 10.1021/acs.joc.0c00927

Rehulka J, Vychodilova K, Krejci P, Gurska S, Hradil P, Hajduch M, et al. Fluorinated derivatives of 2-phenyl-3-hydroxy-4(1H)-quinolinone as tubulin polymerization inhibitors. European Journal of Medicinal Chemistry. 2020;192. ISSN 0223-5234. DOI: 10.1016/j.ejmech.2020.112176

Krcova, L., Rimpelova, S., Havlik, M., Dolensky, B., Vellieux, F., Ruml, T., Martasek, P., Kral, V., Briza, T. Highly selective mitochondrial probes based on fluorinated pentamethinium salts: On two-photon properties and microscopic applications. Dyes and Pigments 2020, 172, 107802. ISSN 0143-7208. DOI: 10.1016/j.dyepig.2019.107802

Talianova, V., Briza, T., Krcova, L., Dolensky, B., Kralova, J., Martasek, P., Kral, V., Havlik, M., Coumarin Troger's base derivatives with cyanine substitution as selective and sensitive fluorescent lysosomal probes. Bioorg. Chem. 2020, 94, 103447. ISSN 0045-2068. DOI: 10.1016/j.bioorg.2019.103447

Antonyova, V., Kejik, Z., Brogyanyi, T., Kaplanek, R., Pajkova, M., Talianova, V., Hromadka, R., Masarik, M., Sykora, D., Miksatkova, L., Martasek, P., Jakubek, M. Role of mtDNA disturbances in the pathogenesis of Alzheimer's and Parkinson's disease. DNA Repair 2020, 91-92, 102871. ISSN 1568-7864. DOI: 10.1016/j.dnarep.2020.102871

Abramenko, N., Kejik, Z., Kaplanek, R., Tatar, A., Brogyanyi, T., Pajkova, M., Sykora, D., Vesela, K., Antonyova, V., Dytrych, P., Ikeda-Saito, M., Martasek, P., Jakubek, M. Spectroscopic study of in situ-formed metallocomplexes of proton pump inhibitors in water. Chem. Biol. Drug Des. 2020. ISSN 1747-0277. DOI: 10.1111/cbdd.13782

Zima, V., Radilová, K., Kožíšek, M., Albiñana, C. B., Karluková, E., Brynda, J., Fanfrlík, J., Flieger, M., Hodek, J., Weber, J., Majer, P., Konvalinka, J., Machara, A. Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors. Eur. J. Med. Chem. 2020, 208, Article Number: 112754. ISSN 0223-5234. DOI: 10.1016/j.ejmech.2020.112754

Šimková,  A., Bušek, P., Šedo, A., Konvalinka, J.:Molecular recognition of fibroblast activation protein for diagnostic and therapeutic applications. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics,1868, Issue 7, 2020, 140409

Mančíková, V., Peschelová, H., Kozlová, V., Ledererová A., Ladungová, A., Verner, J., Loja, T., Folber, F., Mayer, J., Pospíšilová, Š., Šmída, M. Performance of anti-CD19 chimeric antigen receptor T cells in genetically defined classes of chronic lymphocytic leukemia. Journal for ImmunoTherapy of Cancer. Switzerland: Springer International Publishing AG, 2020, roč. 8, č. 1, s. 000471-481. ISSN 2051-1426. doi:10.1136/jitc-2019-000471. ISSN 2051-1426. DOI: 10.1136/jitc-2019-000471

Jašková, Z., Pavlová, Š., Malčíková, J., Brychtová, Y. a Trbušek, M. PRIMA-1MET cytotoxic effect correlates with p53 protein reduction in TP53-mutated chronic lymphocytic leukemia cells. Leukemia Research. Oxford: Pergamon Press, 2020, roč. 89, FEB 2020, s. 1-7. ISSN 0145-2126. DOI: 10.1016/j.leukres.2019.106288
 

Novy, Z., Lobaz, V., Vlk, M., Kozempel, J., Stepanek, P., Popper, M., et al. Head-To-Head Comparison of Biological Behavior of Biocompatible Polymers Poly(Ethylene Oxide), Poly(2-Ethyl-2-Oxazoline) and Poly N-(2-Hydroxypropyl)Methacrylamide as Coating Materials for Hydroxyapatite Nanoparticles in Animal Solid Tumor Model. Nanomaterials. 2020;10(9). ISSN 2079-4991. DOI: 10.3390/nano10091690

Lindomar, J., Albuquerque, C., Sincari, V., Jäger, A., Kucka, J., Humajova, J., Pankrac, J., Paral, P., Heizer, T.,  Janouškova, O., Davidovich, I., Yeshayahu Talmon, Pavla Pouckova, Petr Štěpánek, Ludek Sefc, Martin Hruby, Fernando C. Giacomelli, Eliézer Jäger. Environmentally Responsive Polymersome-Mediated Delivery of Doxorubicin into Tumor Sites Enhances the Therapeutic Efficacy and Reduces Cardiotoxic Effects. Journal of Controlled Release 2020, submitted. ISSN 0168-3659.

Holubová, M., Lobaz, V., Loukotová, L., Rabyk, M., Hromádková, J., Trhlíková, O., Pechrová, Z., Groborz, O., Štěpánek, P., Hrubý, M. Does polysaccharide glycogen behave as a promoter of amyloid fibril formation at physiologically relevant concentrations? Soft Matter, 2020. ISSN 1744-683X. DOI: 10.1039/d0sm01884h

Holubova, M., Lobaz, V., Loukotova, L., Rabyk, M., Hromadkova, J., Trhlıkova, O., Pechrova, Z., Groborz, O., Stepanek, P. and Hruby, M. Chemically modified glycogens: how they influence formation of amyloid fibrils? Soft Matter, 2020. ISSN 1744-683X. DOI: 10.1039/d0sm01829e

Švěc, P., Nový, Z., Kučka, J., Petřík, M., Sedláček, O., Kuchař, M., Lišková, B., Medvedíková, M., Kolouchová, K., Groborz, O., Loukotová, L. Konefał, R., Hajdúch, M. and Hrubý, M. Iodinated Choline Transport-Targeted Tracers.  J. Med. Chem. 2020, 63, 15960−15978. ISSN 0022-2623. DOI: org/10.1021/acs.jmedchem.0c01710

Rahman, W.U., Osickova, A., Klimova, N., Lora, .J, Balashova, N., Osicka, R. Binding of Kingella kingae RtxA Toxin Depends on Cell Surface Oligosaccharides, but Not on β2 Integrins. Int J Mol Sci. 2020 Nov 29;21(23):9092. ISSN 1422-0067. DOI: 10.3390/ijms21239092

Kuban, V., Macek, P., Hritz, J., Nechvatalova, K., Nedbalcova, K., Faldyna, M., Sebo, P., Zidek, L., Bumba, L. Structural Basis of Ca2+-Dependent Self-Processing Activity of Repeat-in-Toxin Proteins. mBio. 2020 Mar 17;11(2):e00226-20. ISSN 2150-7511. DOI: 10.1128/mBio.00226-20

Stanek, O, Linhartova, I, Holubova, J, Bumba, L, Gardian, Z, Malandra, A, Bockova, B, Teruya, S, Horiguchi, Y, Osicka, R, Sebo, P. Production of Highly Active Recombinant Dermonecrotic Toxin of Bordetella Pertussis. Toxins (Basel). 2020 Sep 15;12(9):596. ISSN 2072-6651. DOI: 10.3390/toxins12090596

Bayram, J, Malcova, I, Sinkovec, L, Holubova, J, Streparola, G, Jurnecka, D, Kucera, J, Sedlacek, R, Sebo, P, Kamanova, J. Cytotoxicity of the effector protein BteA was attenuated in Bordetella pertussis by insertion of an alanine residue. PLoS Pathog. 2020 Aug 10;16(8):e1008512. ISSN 1553-7366. DOI: 10.1371/journal.ppat.1008512

Holubová, J., Staněk, O., Brázdilová, L., Mašín, J., Bumba, L., Gorringe, AR, Alexander, F, Šebo P. Acellular Pertussis Vaccine Inhibits Bordetella pertussis Clearance from the Nasal Mucosa of Mice. Vaccines (Basel). 2020 Nov 19;8(4):695. ISSN 2076-393X. DOI: 10.3390/vaccines8040695

Motlova, L., Klimova, N., Fiser, R., Sebo, P., Bumba, L. Continuous Assembly of β-Roll Structures Is Implicated in the Type I-Dependent Secretion of Large Repeat-in-Toxins (RTX) Proteins. J Mol Biol. 2020 Sep 18;432(20):5696-5710. ISSN 0022-2836. DOI: 10.1016/j.jmb.2020.08.020

Masin, J., Osickova, A., Jurnecka, D., Klimova, N., Khaliq, H., Sebo, P., Osicka, R. Retargeting from the CR3 to the LFA-1 receptor uncovers the adenylyl cyclase enzyme-translocating segment of Bordetella adenylate cyclase toxin. J Biol Chem. 2020 Jul 10;295(28):9349-9365. ISSN 0021-9258 DOI: 10.1074/jbc.RA120.013630

Osickova, A., Khaliq, H., Masin, J., Jurnecka, D., Sukova, A., Fiser R., Holubova, J., Stanek, O., Sebo P., Osicka R. Acyltransferase-mediated selection of the length of the fatty acyl chain and of the acylation site governs activation of bacterial RTX toxins. J Biol Chem. 2020 Jul 10;295(28):9268-9280. Epub 2020 May 27. ISSN 0021-9258. DOI: 10.1074/jbc.RA120.014122

Vašíček, T., Spiwok, V., Červený, J., Petrásková, L., Bumba, L., Vrbata, D., Pelantová, H., Křen V., Bojarová P. Regioselective 3-O-Substitution of Unprotected Thiodigalactosides: Direct Route to Galectin Inhibitors. Chemistry. 2020 Aug 3;26(43):9620-9631. ISSN 0947-6539. DOI: 10.1002/chem.202002084.

Filipová, M., Bojarová, P., Rodrigues Tavares, M., Bumba, L., Elling, L., Chytil, P., Gunár, K., Křen, V., Etrych, T., Janoušková, O. Glycopolymers for Efficient Inhibition of Galectin-3: In Vitro Proof of Efficacy Using Suppression of T Lymphocyte Apoptosis and Tumor Cell Migration. Biomacromolecules. 2020 Aug 10;21(8):3122-3133. ISSN 1525-7797. DOI: 10.1021/acs.biomac.0c00515. Epub 2020 Jul 22

Novak, J., Fabrik, I., Jurnecka, D., Holubova, J., Stanek, O., Sebo, P. Bordetella pertussis Acetylome is Shaped by Lysine Deacetylase Bkd1. J Proteome Res. 2020 Sep 4;19(9):3680-3696. ISSN 1535-3893. DOI: 10.1021/acs.jproteome.0c00178

Sukova, A., Bumba, L., Srb, P., Veverka, V., Stanek, O., Holubova, J., Chmelik, J., Fiser, R., Sebo, P., Masin, J. Negative charge of the AC-to-Hly linking segment modulates calcium-dependent membrane activities of Bordetella adenylate cyclase toxin. Biochim Biophys Acta Biomembr. 2020 Sep 1;1862(9):183310. ISSN 0005-2736. DOI: 10.1016/j.bbamem.2020.183310

Petrenko, Y., Vacková, I., Kekulová, K., Chudičková, M., Koči, Z., Turnovcová, K., Skalníková-Kupcová, H., Vodička, P., Kubinová, Š. A Comparative Analysis of Multipotent Mesenchymal Stromal Cells derived from Different Sources, with a Focus on Neuroregenerative Potential. Scientific Reports. 2020. 10(1): 4290. ISSN 2045-2322. DOI: 10.1038/s41598-020-61167-z

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