Journal article Open access Published 2026

Ugi-Tetrazole-Derived α‑Aminomethyl Scaffolds Reveal Unexpected Binding Modes in SARS-CoV‑2 3CLpro

R. van der Straat, R. Oerlemans, Y. Cong, J. Boxma, R.G. Bulai, C. Rio-Berge, L. Koekemoer, T. Zarganes-Tzitzikas, M. Guan, P.G. Marples, F. Reggiori, M. Groves, Alexander Dömling

ACS Medicinal Chemistry Letters 17(4), 856-865 (2026)

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VAN DER STRAAT, R., R. OERLEMANS, Y. CONG, J. BOXMA, R. BULAI, C. RIO-BERGE, L. KOEKEMOER, T. ZARGANES-TZITZIKAS, M. GUAN, P. MARPLES, F. REGGIORI, M. GROVES, A. DÖMLING: Ugi-Tetrazole-Derived α‑Aminomethyl Scaffolds Reveal Unexpected Binding Modes in SARS-CoV‑2 3CLpro. ACS Medicinal Chemistry Letters. 2026, 17(4), 856-865, ISSN: 1948-5875, PMID: 41982734,  PDF.

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