The aim of the project is the technological modernization and upgrade of the large research infrastructure of BBMRI-CZ. The objectives of the project are fully in line with Call No. 02_18_046 Research Infrastructure II, specific objective 1 (SC 1). Modernization will lead to an increase in the reproducibility of basic and translational research in the areas of research into the etiopathogenesis of cancer and other socially significant diseases across various fields of medicine.