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Urban Milan Ph.D.

Journals

HODOŇ, J., L. BORKOVÁ, J. POKORNÝ, A. KAZAKOVA, M. URBAN
Design and synthesis of pentacyclic triterpene conjugates and their use in medicinal research. European Journal of Medicinal Chemistry. 2019, 182, 111653, ISSN: 0223-5234, PMID: 31499360,
POKORNÝ, J., S. KRAJČOVIČOVÁ, M. HAJDÚCH, M. HOLOUBEK, S. GURSKÁ, P. DŽUBÁK, T. VOLNÁ, I. POPA, M. URBAN
Triterpenic azines, a new class of compounds with selective cytotoxicity to leukemia cells CCRF-CEM. Future Medicinal Chemistry. 2018, 10(5), 483-491, ISSN: 1756-8919, PMID: 29424548,
A Synthetic Approach for the Rapid Preparation of BODIPY Conjugates and their use in Imaging of Cellular Drug Uptake and Distribution. Chemistry- A European Journal. 2018, 24(19), 4957-4966, ISSN: 0947-6539, PMID: 29411907,

Master mentorship

Borková Lucie Ph.D.

Modification of the position 2 in betulin, allobetulin and betulinic acid with polar substituents

Status: Graduated from 2012 to 2014.
Hodoň Jiří

Cytotoxic active triterpenes and their mechanism of action

Status: Graduated from 2015 to 2017.
Schwarzová Agnes

Preparation of analogues of platanic and betulinic acid with cytotoxic effect

Status: Ongoing from 2022.

Bachelor mentorship

Kúdelová Kristína

Synthesis of new semisynthetic derivatives of betulin

Status: Graduated from 2021 to 2022.
Šťastná Barbora

Synthesis of triterpenes suitable for their visualization in the cell

Status: Graduated from 2021 to 2022.
Novák Jakub

Visualization of triterpenes in tumor cells

Status: Graduated from 2021 to 2023.

Open positions

Project: Modifications of biologically active molecules leading to improvement of their pharmacological properties
Supervisors: Urban Milan Ph.D., Ranc Václav Ph.D., Polishchuk Pavlo Ph.D., M.Sc.
Available: 3
Intended for: Doctoral training
Project: Research and development of agents for cancer, neurodegenerative and infectious diseases
Supervisors: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
Available: 5
Intended for: Doctoral training