Czech Republic

PETŘÍK, M., E. UMLAUFOVÁ, V. RACLAVSKÝ, A. PALYZOVA, V. HAVLICEK, H. HAAS, Z. NOVÝ, D. DOLEŽAL, M. HAJDÚCH, C. DECRISTOFORO. Imaging of Pseudomonas aeruginosa infection with Ga-68 labelled pyoverdine for positron emission tomography. Scientific Reports. 2018, 8 (1), 15698. ISSN: 2045-2322. IF: 4.122. PMID: 30356077

JAWOREK, H., V. KOUDELÁKOVÁ, J. DRÁBEK, J. VRBKOVÁ, B. ZBORILOVA, I. OBORNA, J. BREZINOVA, R. MAREK, K. HUML, P. VANEK, M. HAJDÚCH. A Head-to-Head Analytical Comparison of Cobas 4800 HPV, PapilloCheck HPV: Screening, and LMNX Genotyping Kit HPV GP for Detection of Human Papillomavirus DNA in Cervical and Cervicovaginal Swabs. The Journal of Molecular Diagnostics. 2018, 20 (6), 849-858. ISSN: 1525-1578. IF: 4.880. PMID: 30165205

AGRAWAL, K., V. DAS, N. TÁBORSKÁ, J. GURSKÝ, P. DŽUBÁK, M. HAJDÚCH. Differential Regulation of Methylation-Regulating Enzymes by Senescent Stromal Cells Drives Colorectal Cancer Cell Response to DNA-Demethylating Epi-Drugs. Stem Cells International. 2018, 6013728. ISSN: 1687-966X. IF: 3.989. PMID: 30158986

TOKARENKO, A., B. LIŠKOVÁ, S. SMOLEN, N. TÁBORSKÁ, M. TICHÝ, S. GURSKÁ, P. PERLÍKOVÁ, I. FRYDRYCH, E. TLOUŠŤOVÁ, P. ZNOJEK, H. MERTLIKOVA-KAISEROVA, L. POSTOVA SLAVETINSKA, R. POHL, B. KLEPETAROVA, N. KHALID, Y. WENREN, R. LAPOSA, P. DŽUBÁK, M. HAJDÚCH, M. HOCEK. Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-fused 7-Deazapurine Ribonucleosides. Journal of Medicinal Chemistry. 2018, 61 (20), 9347-9359. ISSN: 0022-2623. IF: 6.253. PMID: 30281308

AGRAWAL, K., V. DAS, P. VYAS, M. HAJDÚCH. Nucleosidic DNA demethylating epigenetic drugs - A comprehensive review from discovery to clinic. Pharmacology & Therapeutics. 2018, 188, 45-79. ISSN: 0163-7258. IF: 11.127. PMID: 29454856

FLODROVÁ, P., P. FLODR, T. PIKA, J. VYMETAL, D. HOLUB, P. DŽUBÁK, M. HAJDÚCH, V. SCUDLA. Cardiac amyloidosis: from clinical suspicion to morphological diagnosis. Pathology. 2018, 50 (3), 261-268. ISSN: 0031-3025. IF: 2.709. PMID: 29448998

POKORNÝ, J., S. KRAJČOVIČOVÁ, M. HAJDÚCH, M. HOLOUBEK, S. GURSKÁ, P. DŽUBÁK, T. VOLNÁ, I. POPA, M. URBAN. Triterpenic azines, a new class of compounds with selective cytotoxicity to leukemia cells CCRF-CEM. Future Medicinal Chemistry. 2018, 10 (5), 483-491. ISSN: 1756-8919. IF: 3.566. PMID: 29424548

MAYA-MENDOZA, A., P. MOUDRÝ, J. MERCHUT-MAYA, M. LEE, R. STRAUSS, J. BÁRTEK. High speed of fork progression induces DNA replication stress and genomic instability. Nature. 2018, 559 (7713), 279-284. ISSN: 0028-0836. IF: 41.577. PMID: 29950726

MRAZKOVA, B., R. DZIJAK, T. IMRICHOVA, L. KYJACOVA, P. BARATH, P. DŽUBÁK, D. HOLUB, M. HAJDÚCH, Z. NAHACKA, L. ANDERA, P. HOLICEK, P. VASICOVA, O. SAPEGA, J. BÁRTEK, Z. HODNY. Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence. Aging. 2018, 10 (3), 432-462. ISSN: 1945-4589. IF: 4.867. PMID: 29615539

BÜRGLOVÁ, K., G. RYLOVÁ, A. MARKOS, H. PŘICHYSTALOVÁ, M. SOURAL, M. PETRÁČEK, M. MEDVEDÍKOVÁ, G. TEJRAL, B. SOPKO, P. HRADIL, P. DŽUBÁK, M. HAJDÚCH, J. HLAVÁČ. Identification of Eukaryotic Translation Elongation Factor 1-α 1 Gamendazole-Binding Site for Binding of 3-Hydroxy-4(1 H)-quinolinones as Novel Ligands with Anticancer Activity. Journal of Medicinal Chemistry. 2018, 61 (7), 3027-3036. ISSN: 0022-2623. IF: 6.259. PMID: 29498519

OSICKOVA, A., N. BALASHOVA, J. MASIN, M. SULC, J. RODEROVA, T. WALD, A. C. BROWN, E. KOUFOS, E. H. CHANG, A. GIANNAKAKIS, E. T. LALLY, R. OSICKA. Cytotoxic activity of Kingella kingae RtxA toxin depends on post-translational acylation of lysine residues and cholesterol binding. Emerging Microbes & Infections. 2018, 7 (1), 178. ISSN: 2222-1751. IF: 6.032. PMID: 30405113

BUMBA, L., J. MASIN, A. OSICKOVA, R. OSICKA, P. SEBO. Bordetella Pertussis Adenylate Cyclase Toxin Does Not Possess a Phospholipase A Activity; Serine 606 and Aspartate 1079 Residues Are Not Involved in Target Cell Delivery of the Adenylyl Cyclase Enzyme Domain. Toxins (Basel). 2018, 10 (6), pii: E245. ISSN: 2072-6651. IF: 3.273. PMID: 29914160

HASAN, S., N. N. KULKARNI, A. ASBJARNARSON, I. LINHARTOVA, R. OSICKA, P. SEBO, G. H. GUDMUNDSSON. Bordetella pertussis Adenylate Cyclase Toxin Disrupts Functional Integrity of Bronchial Epithelial Layers. Infection and Immunity. 2018, 86 (3), pii: e00445-17. ISSN: 1098-5522. IF: 3.256. PMID: 29203545
BUMBA, L., D. LAAF, V. SPIWOK, L. ELLING, V. KŘEN, P. BOJAROVÁ. Poly-N-Acetyllactosamine Neo-Glycoproteins as Nanomolar Ligands of Human Galectin-3: Binding Kinetics and Modeling. International Journal of Molecular Sciences. 2018, 19 (2). pii: E372. ISSN: 1422-0067. IF: 3.687 PMID: 29373511

JURNECKA, D., P. MAN, P. SEBO, L. BUMBA. Bordetella pertussis and Bordetella bronchiseptica filamentous hemagglutinins are processed at different sites. FEBS Open Bio. 2018, 8 (8), 1256-1266. ISSN: 2211-5463. IF: 4.530. PMID: 30087831

KOČÍ, Z., T. BORÁŇ, P. KRŮPA, Š. KUBINOVÁ. The Current State of Advanced Therapy Medicinal Products in the Czech Republic. Human Gene Therapy Clinical Development. 2018, 29(3), 132-147. ISSN: 2324-8637, 2324-8645. IF: 2.431. PMID: 29869533

KRŮPA, P., I. VACKOVÁ, J. RŮŽIČKA, ZÁVIŠKOVÁ, K., DUBIŠOVÁ, J., KOČÍ, Z., TURNOVCOVÁ, K., URDZÍKOVÁ, L., KUBINOVÁ, Š., ŘEHÁK, S., JENDELOVÁ, P. The Effect of Human Mesenchymal Stem Cells Derived from Wharton's Jelly in Spinal Cord Injury Treatment Is Dose-Dependent and Can Be Facilitated by Repeated Application. International Journal of Molecular Sciences. 2018, 19 (5), pii: E1503. ISSN: 1422-0067. IF: 3.687. PMID: 29772841

JAKUBEK, M., Z. KEJÍK, R. KAPLÁNEK, H. VESELÁ, D. SÝKORA, P. MARTÁSEK, V. KRÁL. Perimidine-based synthetic receptors for determination of copper(II) in water solution. Supramolecular Chemistry. 2018, 30 (3), 218-226. ISSN: 1061-0278. IF: 1.451.

D'ACUNTO, C. W., R. KAPLANEK, H. GBELCOVA, Z. KEJIK, T. BRIZA, L. VASINA, M. HAVLIK, T. RUML, V. KRAL. Metallomics for Alzheimer's disease treatment: Use of new generation of chelators combining metal-cation binding and transport properties. European Journal of Medicinal Chemistry. 2018, 150, 140-155. ISSN: 1768-3254. IF: 4.816. PMID: 29525434

BREZANIOVA, I., K. ZARUBA, J. KRALOVA, A. SINICA, H. ADAMKOVA, P. ULBRICH, P. POUCKOVA, M. HRUBY, P. STEPANEK, V. KRAL. Silica-based nanoparticles are efficient delivery systems for temoporfin. Photodiagnosis and Photodynamic Therapy. 2018, 21, 275-284. ISSN: 1572-1000. IF: 2.895. PMID: 29288831

TOM, N., O. TOM, J. MALCIKOVA, S. PAVLOVA, B. KUBESOVA, T. RAUSCH, M. KOLARIK, V. BENES, V. BYSTRY, S. POSPISILOVA. ToTem: a tool for variant calling pipeline optimization. BMC Bioinformatics. 2018, 19 (1), 243. ISSN: 1471-2105. IF: 2.213. PMID: 29940847

KUBEŠOVÁ, B., Š. PAVLOVÁ, J. MALČÍKOVÁ, J. KABÁTHOVÁ, L. RADOVÁ, N. TOM, B. TICHÝ, K. PLEVOVÁ, B. KANTOROVÁ, K. FIEDOROVÁ, M. SLÁVIKOVÁ, V. BYSTRÝ, J. KISSOVÁ, B. GISSLINGER, H. GISSLINGER, M. PENKA, J. MAYER, R. KRALOVICS, Š. POSPÍŠILOVÁ, M. DOUBEK. Low-burden TP53 mutations in chronic phase of myeloproliferative neoplasms: association with age, hydroxyurea administration, disease type and JAK2 mutational status. Leukemia. 2018, 32 (2), 450-461. ISSN: 1476-5551. IF=10,023. PMID: 28744014

ŠÁNA, J., P. BUŠEK, P. FADRUS, A. BEŠŠE, L. RADOVÁ, M. VEČEŘA, S. REGULI, L. STOLLINOVA SROMOVA, M. HILŠER, R. LIPINA, R. LAKOMÝ, L. KŘEN, M. SMRČKA, A. ŠEDO, O. SLABÝ. Identification of microRNAs differentially expressed in glioblastoma stem-like cells and their association with patient survival. Scientific Reports. 2018, 8 (1): 2836. ISSN: 2045-2322. IF=4,122. PMID: 29434344

BUSEK, P., R. MATEU, M. ZUBAL , L. KOTACKOVA, A. SEDO. Targeting fibroblast activation protein in cancer - Prospects and caveats. Frontiers in bioscience (Landmark edition). 2018, 23, 1933-1968. ISSN: 1093-4715. IF: 2.349. PMID: 29772538

VETRIK, M., J. MATTOVA, H. MACKOVA, J. KUCKA, P. POUCKOVA, O. KUKACKOVA, J. BRUS, S. EIGNER-HENKE, O. SEDLACEK, L. SEFC, P. STEPANEK, M. HRUBY. Biopolymer strategy for the treatment of Wilson's disease. Journal of Controlled Release. 2018, 273:131-138. ISSN: 1873-4995. IF: 7.877. PMID: 29407674

BRUS, J., J. CZERNEK, M. HRUBY, P. SVEC, L. KOBERA, S. ABBRENT, M. URBANOVA. Efficient Strategy for Determining the Atomic-Resolution Structure of Micro- and Nanocrystalline Solids within Polymeric Microbeads: Domain-Edited NMR Crystallography. Macromolecules. 2018, 51 (14), 5364−5374. ISSN: 0024-9297, 1520-5835. IF: 5.914. 

RABYK, M., A. DESTEPHEN, A. LAPP, S. KING, L. NOIREZ, L. BILLON, M. HRUBY, O. BORISOV, P. STEPANEK, E. DENIAU. Interplay of Thermosensitivity and pH Sensitivity of Amphiphilic Block−Gradient Copolymers of Dimethylaminoethyl Acrylate and Styrene. Macromolecules. 2018, 51, 5219−5233. ISSN: 0024-9297. IF: 5.914.

VETRIK, M., M. PARIZEK, D. HADRABA, O. KUKACKOVA, J. BRUS, H. HLIDKOVA, L. KOMANKOVA, J. HODAN, O. SEDLACEK, M. SLOUF, L. BACAKOVA, M. HRUBY:  Porous Heat-Treated Polyacrylonitrile Scaffolds for Bone Tissue Engineering. ACS Applied Materials and Interfaces. 2018, 10 (10), 8496−8506.  ISSN: 1944-8252. IF: 8.097. PMID: 29437373

LOBAZ, V., M. HLADÍK, M. STEINHART, A. PARUZEL, P. ČERNOCH, J. PÁNEK, M. VETRÍK, D. JIRÁK, M. JIRÁTOVÁ, O. POP-GEORGIEVSKI, M. ŠLOUF, S. GARCIA-ARGOTE, G. PIETERS, E. DORIS, M. HRUBÝ. Tungsten (VI) based "molecular puzzle" photoluminescent nanoparticles easily covered with biocompatible natural polysaccharides via direct chelation. Journal of Colloid and Interface Science. 2018, 512, 308-317. ISSN: 0021-9797. IF: 5.091. PMID: 29078182

BARTHELDYOVA, E., P. TURANEK KNOTIGOVA, K. ZACHOVÁ, V. MAŠEK, P. KULICH, R. EFFENBERG, D. ZYKA, F. HUBATKA, J. KOTOUCEK, H. CELECHOVSKA, R. HEZOVA, A. TOMECKOVA, E. MASKOVA, M. FOJTIKOVA, S. MACAULAY, P. BYSTRICKY, E. PAULOVICOVA, L. DROZ, M. LEDVINA, M. RAŠKA,  J. TURANEK. N-Oxy lipid-based click chemistry for orthogonal coupling of mannan onto nanoliposomes prepared by microfluidic mixing: Synthesis of lipids, characterisation of mannan-coated nanoliposomes and in vitro stimulation of dendritic cells. Carbohydrate Polymers. 2019, 207, 521-532. ISSN: 0144-8617. IF: 5.158. PMID: 30600036

DE LA FUENTE, G., F. TRALDI, J. ŠIROKÁ, A. KRETOWSKI, M. CIBOROWSKI, A. OTERO, C. BARBAS, J. GODZIEN. Characterization and annotation of oxidized glycerophosphocholines for non-targeted metabolomics with LC-QTOF-MS data. Analytica Chimica Acta. 2018, 1037, 358-369. ISSN: 0003-2670. IF: 5.123. PMID: 30292312

CAMPA, D., M. MATARAZZI, W. GREENHALF, M. BIJLSMA, K. SAUM, C. PASQUALI, H. VAN LAARHOVEN, A. SZENTESI, F. FEDERICI, P. VODICKA, N. FUNEL, R. PEZZILLLI, H. BUENO-DE-MESQUITA, L. VODICKOVA, D. BASSO, O. OBAZZE, T. HACKERT, P. SOUCEK, K. CUK, J. KAISER, C. SPERTI, M. LOVECEK, G. CAPURSO, B. MOHELNÍKOVÁ DUCHOŇOVÁ, K. KHAW, A. KONIG, J. KUPCINSKAS, R. KAAKS, F. BAMBI, L. ARCHIBUGI, A. MAMBRINI, G. CAVESTRO, S. LANDI, P. HEGYI, J. IZBICKI, D. GIOFFREDA, C. ZAMBON, F. TAVANO, R. TALAR-WOJNAROWSKA, K. JAMROZIAK, T. KEY, G. FAVE, O. STROBEL, L. JONAITIS, A. ANDRUILLI, R. LAWLOR, F. PIROZZI, V. KATZKE, C. VALSUANI, Y. VASHIST, H. BRENNER, F. CANZIAN. Genetic determinants of telomere length and risk of pancreatic cancer: a PANDoRA study. International Journal of Cancer.  2018, 144 (6), 1275-1283. ISSN: 0020-7136.  IF: 7.360. PMID: 30325019

VRZALIKOVA, K., M. IBRAHIM, E. NAGY, M. VOCKERODT, T. PERRY, W. WEI, C. WOODMAN, P. MURRAY. Co-Expression of the Epstein-Barr Virus-Encoded Latent Membrane Proteins and the Pathogenesis of Classic Hodgkin Lymphoma.  Cancers.  2018, 10 (9), pii: E285.  ISSN: 2072-6694.  IF: 5.326. PMID: 30149502

DE CASTRO, C. E., C. A. S. RIBEIRO, A. C. ALAVARSE, L. J. C. ALBUQUERQUE, M. C. C. DA SILVA, E. JAGER, F. SURMAN, V. SCHMIDT, C. GIACOMELLI, F. C. GIACOMELLI. Nanoparticle−Cell Interactions: Surface Chemistry Effects on the Cellular Uptake of Biocompatible Block Copolymer Assemblies. Langmuir. 2018, 34 (5), 2180-2188. ISSN: 1944-8252. IF: 3.789. PMID: 29338258

D. KLEPAC, H. KOSTKOVÁ, S. PETROVA, P. CHYTIL, T. ETRYCH, S. KEREÏCHE, I. RAŠKA, D. A. WEITZ, S. K. FILIPPOV. Interaction of spin-labeled HPMA-based nanoparticles with human blood plasma proteins – the introduction of protein-corona-free polymer nanomedicine. Nanoscale. 2018, 10 (13), 6194-6204. ISSN: 2040-3364, 2040-3372. IF: 7.233. PMID: 29560983

K. KOLOUCHOVA, O. SEDLACEK, D. JIRAK, D. BABUKA, J. BLAHUT, J. KOTEK, M. VIT, J. TROUSIL, M. HRUBY. Self-Assembled Thermoresponsive Polymeric Nanogels for FMR Imaging. Biomacromolecules. 2018, 19 (8) 3515-3524. ISSN: 1526-4602. IF: 5.738. PMID: 30011367

TROUSIL, J., V. ULMANN, M. HRUBY. Fluorescence & bioluminescence in the quest for imaging, probing & analysis of mycobacterial infections. Future Microbiology. 2018, 13, 933-951. ISSN: 1746-0921. IF: 3.190. PMID: 29893148

KUBEŠOVÁ, B., Š. PAVLOVÁ, J. MALČÍKOVÁ, J. KABÁTHOVÁ, L. RADOVÁ, N. TOM, B. TICHÝ., K. PLEVOVÁ, B. KANTOROVÁ, K. FIEDOROVÁ, M. SLÁVIKOVÁ, V. BYSTRÝ, J. KISSOVÁ, B. GISSLINGER, H. GISSLINGER, M. PENKA, J. MAYER, R. KRALOVICS, Š. POSPÍŠILOVÁ, M. DOUBEK. Low-burden TP53 mutations in chronic phase of myeloproliferative neoplasms: association with age, hydroxyurea administration, disease type and JAK2 mutational status. Leukemia. 2018, 32 (2), 450-461. ISSN: 1476-5551. IF: 10.023. PMID: 28744014

MOJZIKOVA, R., P. KOŘALKOVÁ, D. HOLUB, Z. SAXOVA, D. POSPÍŠILOVÁ, D. PROCHAZKOVA, P. DŽUBÁK, M. HORVÁTHOVÁ, V. DIVOKÝ. Two novel mutations (p.(Ser160Pro) and p.(Arg472Cys)) causing glucose-6-phosphate isomerase deficiency are associated with erythroid dysplasia and inappropriately suppressed hepcidin. Blood cells, molecules & diseases. 2018, 69, 23-29. ISSN: 1096-0961. IF: 1.882. PMID: 28803808