Journal article Open access Published 2026

Optimization of Azaspirooxindolinone-based PROTACs targeting BTK: Synthesis, kinase profiling, and degradation analysis

N. Rampeesa, R. Gundla, Soňa Gurská, S. Yadam, S. Tangallapalli, S. Anugu, Juan Bautista De Sanctis, Petr Džubák, Marián Hajdúch, N. Katari, Viswanath Das, S. Jonnalagadda

Results in Chemistry 23, 103145 (2026)

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RAMPEESA, N., R. GUNDLA, S. GURSKÁ, S. YADAM, S. TANGALLAPALLI, S. ANUGU, J. DE SANCTIS, P. DŽUBÁK, M. HAJDÚCH, N. KATARI, V. DAS, S. JONNALAGADDA: Optimization of Azaspirooxindolinone-based PROTACs targeting BTK: Synthesis, kinase profiling, and degradation analysis. Results in Chemistry. 2026, 23, 103145, ISSN: 2211-7156, PDF.

Optimization of Azaspirooxindolinone-based PROTACs targeting BTK: Synthesis, kinase profiling, and degradation analysis

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