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Journal article Open access Published 2026

Structure-based design of a 1H-Tetrazole-containing scaffold for Caspase-1 inhibition: Synthesis, biological evaluation, and preliminary in Vivo studies

Authors

A.L. Chandgude, G. Loriga, A. Beccu, F.A. Iannotti, E. Pagano, R. Capasso, Riccardo Fusco, P. Spanu, F. Ulgheri, Alexander Dömling

Bioorganic & Medicinal Chemistry 143, 118794 (2026)

Cite this publication

CHANDGUDE, A., G. LORIGA, A. BECCU, F. IANNOTTI, E. PAGANO, R. CAPASSO, R. FUSCO, P. SPANU, F. ULGHERI, A. DÖMLING: Structure-based design of a 1H-Tetrazole-containing scaffold for Caspase-1 inhibition: Synthesis, biological evaluation, and preliminary in Vivo studies. Bioorganic & Medicinal Chemistry. 2026, 143, 118794, ISSN: 0968-0896, PMID: 42700635,  PDF.

Details

ISSN
0968-0896

Authors from EATRIS