Srovnal Josef M.D., Ph.D.

Journals

BALIK, V., H. SLAVÍK, J. SROVNAL
In Reply: Transcriptomic Profiling Revealed Lnc-GOLGA6A-1 as a Novel Prognostic Biomarker of Meningioma Recurrence. Neurosurgery. 2023, 19(3), e74-e75, ISSN: 0148-396X, PMID: 36700746,
STEJSKAL, P., H. GODARZI, J. SROVNAL, M. HAJDÚCH, L. VAN ´T VEER, M. MAGBUNUA
Circulating tumor nucleic acids: biology, release mechanisms, and clinical relevance. Molecular Cancer. 2023, 22(1), 15, ISSN: 1476-4598, PMID: 36681803,
VIDLAŘOVÁ, M., E. BERTA, P. PRASIL, A. PROKOPOVÁ, S. GURSKÁ, M. KHOYLOU, A. ŘEHULKOVÁ, P. KOUŘILOVÁ, J. CHUDÁČEK, M. SZKORUPA, J. KLEIN, J. ŠKARDA, J. SROVNAL, M. HAJDÚCH
Cannabinoid receptor 2 expression in early-stage non-small cell lung cancers identifies patients with good prognosis and longer survival. Translational Lung Cancer Research. 2022, 11(10), 2040-2050, ISSN: 2218-6751, PMID: 36386452,

Books & book chapters

BOUCHALOVÁ, K., M. HAJDÚCH, J. BOUCHAL, A. HLOBILKOVA, M. HOUDOVÁ MEGOVÁ, M. HUDCOVÁ, V. KOUDELÁKOVÁ, J. MEDALOVA, J. SROVNAL, R. TROJANEC
Prediktivní a prognostická onkologie, 1. vyd, Olomouc, Univerzita Palackého v Olomouci, 2016, 122 s, Dedication: CZ.1.07/2.3.00/09.0089, ISBN: 978-80-244-3188-8,
CIBIČEK, N., J. VACEK, M. BERANEK, P. DŽUBÁK, Z. HEŘMANOVÁ, P. KOSINA, M. KUBALA, M. NOVÁK, B. PAPOUSKOVA, J. SROVNAL, J. VÁVROVÁ, J. VOSTALOVA, M. ZATLOUKALOVA, H. ŽIVNÁ
Hmotnostní spektrometrie, 1. vyd, Olomouc, Univerzita Palackého v Olomouci, 2014, 2.2, 34-40, ISBN: 978-80-244-3951-8,
CIBIČEK, N., J. VACEK, M. BERANEK, P. DŽUBÁK, Z. HEŘMANOVÁ, P. KOSINA, M. KUBALA, M. NOVÁK, B. PAPOUSKOVA, J. SROVNAL, J. VÁVROVÁ, J. VOSTALOVA, M. ZATLOUKALOVA, H. ŽIVNÁ
Elektrochemické metody, (bio)senzory a čipové platformy, 1. vyd, Olomouc, Univerzita Palackého v Olomouci, 2014, 2.3, 43-44, ISBN: 978-80-244-3951-8,

Master mentorship

Jančovičová Jana

Gene Expression Profiling in Patients With Esophageal Cancer

Status: Graduated from 2012 to 2012.
Resutíková Lucie

Novel Markers for theDetection of Minimal Residual Disease in Pancreatic Cancer Patients

Status: Graduated from 2010 to 2010.

Bachelor mentorship

Lišková Veronika

Microsatellite Instability in Colorectal Cancer

Status: Graduated from 2009 to 2009.
Bačová Zuzana M.Sc.

Gene expression profiling in hematological malignancies

Status: Graduated from 2013 to 2013.
Ondrouch Jakub B.Sc.

Gene Expression Profiling in Gastrointestinal Tumors

Status: Graduated from 2013 to 2013.

Open positions

Project: Diagnostics and therapy of rare diseases
Supervisors: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: New prognostic and predictive factors in solid tumors
Supervisors: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
Project: New prognostic and predictive factors in solid tumors
Supervisors: Srovnal Josef M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: Cancer is the second leading cause of death in the western countries. Early diagnosis and targeted therapy improve the therapeutic outcome. With the emergence of new biotechnologies, diagnosis can be made early and precisely, and the knowledge of tumor molecular genetics can identify the most appropriate therapy for a particular patient. The sensitivity of modern molecular methods makes it possible to characterize the tumor properties from sites remote from the primary tumor using patient's blood. The subject of the offered study program is the identification of new prognostic and predictive biomarkers of cancer using liquid biopsies. This is particularly the analysis of circulating tumor cells (CTCs), circulating free tumor DNA (ctDNA) and circulating miRNAs. The aim of the project is to further implement a liquid biopsy concept into the diagnosis and therapy monitoring of solid tumors, especially colorectal, breast, lung and CNS tumors. These include therapy response and resistance monitoring, identifying new therapeutic targets and estimating disease prognosis. The project will provide training in widely-used, transferable techniques, including circulation tumor cells capture system, digital droplet PCR, reverse-transcription qPCR, RNA-seq, single cell analyses, xenografts models and other multi-omics methods. We are looking for candidates with a background in Molecular Biology, Medicine, Cell Biology or a related area, who are enthusiastic about investigating novel approaches in cancer diagnostic that have significant potential for public health.
Project: Diagnosis and treatment of rare diseases
Supervisors: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: New prognostic and predictive factors in solid tumors
Supervisors: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D., Koudeláková Vladimíra Ph.D.
Available: 3
Intended for: Doctoral training
Project: Liquid biopsies in experimental and clinical oncology
Supervisors: Srovnal Josef M.D., Ph.D., Koudeláková Vladimíra Ph.D.
Available: 2
Intended for: Doctoral training