Guan Zhirui

Groups: DOCTORAL STUDENT, IMTM, LEM, STAFF

Discovery and development of novel macrocycles via Multicomponent reactions

Specialization: Molecular and Translational Medicine

Status: Ongoing from 2023.

MOREIRA PEREIRA, T., A. REYES ROMERO, M. VAN DER LAAN, Z. GUAN, R. OERLEMANS, M. GROVES, M. MORI, F. MENEGHETTI, A. DÖMLING

Structural and Biophysical Characterization of Aminobenzo[ d]isothiazole 1,1-Dioxide SOS1 Ligands. ACS Medicinal Chemistry Letters. 2026, 17(8), 1895-1900, ISSN: 1948-5875, PMID: 42621470, PDF.

PATIL, P., R. FUSCO, I. CAPRIELLO, Z. GUAN, A. BHALKIKAR, S. GIBBONS, T. KORBA, S. BASKHYRTSEV, O. TKACHENKO, A. DÖMLING

Precipitation-first synthesis and deep profiling of a 1200-member acrylamide library for covalent drug discovery. Green Chemistry . 2025, 27(45), 14640-14647, ISSN: 1463-9262, PMID: 41181219, PDF.

Guan Zhirui

Doctoral training

Journals