De Sanctis Juan Bautista Ph.D.
About me
I was initially formed in Biochemistry (Temple University), and then I did doctoral studies in physiological sciences, specialising in Biochemistry, Metabolism and immunology. I was a professor for more than 30 years at the Faculty of Medicine and the Institute of Immunology of the Faculty of Medicine of Universidad Central de Venezuela. My big area of expertise is inflammation, with ample background in immune response, cell metabolism, lipidomic, signal transduction and pharmacology. Currently, I am involved in a project on Cancer and immune response and others in Covid and long Covid (pending funding).
Journals
Antimalarial, antiproliferative, and apoptotic activity of quinoline-chalcone and quinoline-pyrazoline hybrids. A dual action.
Medical Chemistry Research.
2019,
28(11),
2050-2066,
ISSN: 1054-2523,
Synthesis and biological activity of 2-[2-(7-chloroquinolin-4-ylthio)-4-methylthiazol-5-yl]-N-phenylacetamide derivatives as antimalarial and cytotoxic agents.
Journal of Chemical Research.
2020,
44(5-6),
305-314,
ISSN: 1747-5198,
Optimization of Azaspirooxindolinone-based PROTACs targeting BTK: Synthesis, kinase profiling, and degradation analysis.
Results in Chemistry.
2026,
23,
103145,
ISSN: 2211-7156,
PDF.
Open positions
| Project: | Research and development of agents for cancer, neurodegenerative and infectious diseases |
|---|---|
| Supervisors: | De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D. |
| Available: | 5 |
| Intended for: | Doctoral training |