Publications

Published in Top 10% journals in the field

ŘEZNÍČKOVÁ, E., S. KRAJČOVIČOVÁ, M. PERINA, A. KOVALOVA, M. SOURAL, V. KRYŠTOF
Modulation of FLT3-ITD and CDK9 in acute myeloid leukaemia cells by novel proteolysis targeting chimera (PROTAC). European Journal of Medicinal Chemistry. 2022, 243, 114792, ISSN: 0223-5234, PMID: 36191408,  PDF.
HODOŇ, J., I. FRYDRYCH, Z. TRHLÍKOVÁ, J. POKORNÝ, L. BORKOVÁ, S. BENICKÁ, M. VLK, B. LIŠKOVÁ, A. KUBÍČKOVÁ, M. MEDVEDÍKOVÁ, M. PISÁR, J. ŠAREK, V. DAS, A. LIGASOVÁ, K. KOBERNA, P. DŽUBÁK, M. HAJDÚCH, M. URBAN
Triterpenoid pyrazines and pyridines - Synthesis, cytotoxicity, mechanism of action, preparation of prodrugs. European Journal of Medicinal Chemistry. 2022, 243, 114777, ISSN: 0223-5234, PMID: 36174412,  PDF.
LEISCHNER FIALOVA, J., K. HONIGOVA, M. RAUDENSKA, L. MIKSATKOVA, R. ZOBALOVA, J. NAVRATIL, J. SMIGOVA, T. RAMJI MOTURU, T. VICAR, J. BALVAN, K. VESELA, N. ABRAMENKO, Z. KEJIK, R. KAPLANEK, J. GUMULEC, D. ROSEL, P. MARTASEK, J. BRABEK, M. JAKUBEK, J. NEUZIL, M. MASARIK
Pentamethinium salts suppress key metastatic processes by regulating mitochondrial function and inhibiting dihydroorotate dehydrogenase respiration. Biomedicine & Pharmacotherapy. 2022, 154, 113582, ISSN: 0753-3322, PMID: 36055111,
JORDA, R., L. HAVLÍČEK, M. PERINA, V. VOJÁČKOVÁ, T. POSPÍŠIL, S. DJUKIC, J. SKERLOVA, J. GRÚZ, N. RENESOVA, P. KLENER, P. ŘEZÁČOVÁ, M. STRNAD, V. KRYŠTOF
3,5,7-Substituted Pyrazolo[4,3- d]Pyrimidine Inhibitors of Cyclin-Dependent Kinases and Cyclin K Degraders. Journal of Medicinal Chemistry. 2022, 65(13), 8881-8896, ISSN: 0022-2623, PMID: 35749742,
SIKOROVÁ, K., S. MOON, H. YOON, A. STRNAD, J. SONG, M. PETŘEK
HLA class II variants defined by next generation sequencing are associated with sarcoidosis in Korean patients. Scientific Reports. 2022, 12(1), 9302, ISSN: 2045-2322, PMID: 35661780,
KLOS, D., M. DUŠEK, E. SAMOLOVA, M. ZATLOUKAL, V. NOZKOVA, N. NESNAS, L. PLACKOVA, R. KOPRNA, Z. SPISEK, H. VYLICILOVA, O. PLIHAL, K. DOLEZAL, J. VOLLER, A. KADLECOVA, M. STRNAD, L. PLÍHALOVÁ
New Water-Soluble Cytokinin Derivatives and Their Beneficial Impact on Barley Yield and Photosynthesis. Journal of Agricultural and Food Chemistry. 2022, 70(23), 7288-7301, ISSN: 0021-8561, PMID: 35658447,
ZACHOVÁ, K., J. JEMELKOVA, P. KOSZTYU, Y. OHYAMA, K. TAKAHASHI, J. ZADRAZIL, J. ORSAG, K. MATOUSOVIC, D. GALUSZKOVÁ, N. PETEJOVA, J. MESTECKY, M. RAŠKA
Galactose-Deficient IgA1 B cells in the Circulation of IgA Nephropathy Patients Carry Preferentially Lambda Light Chains and Mucosal Homing Receptors. Journal of the American Society of Nephrology. 2022, 33(5), 908-917, ISSN: 1046-6673, PMID: 35115327,
WOLRAB, D., R. JIRASKO, E. CIFKOVA, M. HORING, D. MEI, M. CHOCHOLOUSKOVA, O. PETERKA, J. IDOWIAK, T. HRNCIAROVA, L. KUCHAR, R. AHRENDS, R. BRUMAROVÁ, D. FRIEDECKÝ, G. VIVO-TRUYOLS, P. SKRHA, J. SKRHA, R. KUCERA, B. MELICHAR, G. LIEBISCH, R. BURKHARDT, M. WENK, A. CAZENAVE-GASSIOT, P. KARASEK, I. NOVOTNY, K. GREPLOVA, R. HRSTKA, M. HOLCAPEK
Lipidomic profiling of human serum enables detection of pancreatic cancer. Nature Communications. 2022, 13(1), 124, ISSN: 2041-1723, PMID: 35013261,
RAFFAELE, M., K. KOVACOVICOVA, T. BIAGINI, O. LO RE, J. FROHLICH, S. GIALLONGO, J. NHAN, A. GIANNONE, D. CABIBI, M. IVANOV, A. TONCHEV, M. MISTRÍK, M. LACEY, P. DŽUBÁK, S. GURSKÁ, M. HAJDÚCH, J. BÁRTEK, T. MAZZA, V. MICALE, S. CURRAN, M. VINCIGUERRA
Nociceptin/orphanin FQ opioid receptor (NOP) selective ligand MCOPPB links anxiolytic and senolytic effects. Geroscience. 2021, 44(1), 463-483, ISSN: 2509-2715, PMID: 34820764,
MOUDRÝ, P., K. CHROMÁ, S. BURSAC, S. VOLAREVIC, J. BÁRTEK
RNA-interference screen for p53 regulators unveils a role of WDR75 in ribosome biogenesis. Cell Death and Differentiation. 2022, 29(3), 687-696, ISSN: 1350-9047, PMID: 34611297,