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Akademický titul: MSc.
Telefon: 585 632 144
Skupiny: BAKALÁŘSKÝ STUDENT, DOKTORSKÝ STUDENT, ÚMTM, LEM, MAGISTERSKÝ STUDENT, PERSONÁL

Doktorské studium

Cytotoxic drugs molecular target identification by methods of cell biology and proteomics

Molecular target identification of biologically active molecules is a key factor facilitating rational design and preclinical development of potential drugs. Methods of cellular biology, chemical proteomics and mass spectrometry are developed and used for its purposes.

Specializace: Pediatrie
Stav: Ongoing od 2016.

Magisterské studium

Proteomic profile of CCRF-CEM cell line treated by 5-fluorouracil

Stav: Absolvoval od 2014 do 2016.

Bakalářské studium

Determination of the efficacy of 5-fluorouracil on line CCRF-CEM T

Stav: Graduated od 2014 do 2014.

O mně

I am a research assistant and Ph.D. candidate at the Institute of Molecular and Translational Medicine in Olomouc, Czech Republic. Since 2016 I have been participating in the research program Chemical Biology and Experimental Therapeutics, mainly focusing on new methods for molecular target identification, such as microscopy and proteomics methods. I joined the multi-omics group in 2020 and currently working on the proteomics part of the EATRIS-Plus project.

Journals

Terpenes and Terpenoids Conjugated with BODIPYs: An Overview of Biological and Chemical Properties. Journal of Natural products. 2024, 87(4), 1306-1319, ISSN: 0163-3864, PMID: 38482846,  PDF.
BARUCIC, D., S. KAUSHIK, J. KYBIC, J. STANKOVÁ, P. DŽUBÁK, M. HAJDÚCH
Characterization of drug effects on cell cultures from phase-contrast microscopy images. Computers in Biology and Medicine. 2022, 151, 106171, ISSN: 0010-4825, PMID: 36306582,
PORUBSKÝ, M., S. GURSKÁ, J. STANKOVÁ, M. HAJDÚCH, P. DŽUBÁK, J. HLAVÁČ
Amino-BODIPY as the ratiometric fluorescent sensor for monitoring drug release or "power supply" selector for molecular electronics. RSC Advances. 2019, 9(43), 25075-25083, ISSN: 2046-2069, PMID: 35528670,

Books & book chapters

Reporters for subcellular localization and image analysis , 1.vyd., Olomouc, Palacky University, 2021, 19, 141-146, Dedication: LO1304, ISBN: 978-80-244-6049-9,

Master mentorship

Křesťanová Eliška

Development of DIA method useful for plasma proteomic profiling of large sample cohort

Stav: Probíhající od 2022.

Bachelor mentorship

Burgetová Ječmeňová Kateřina

Spectroscopic characteristics used drugs and their use in the identification of molecular targets

Stav: Absolvoval od 2016 do 2018.

Hladíková Eliška

Reporter lentiviral systems for subcellular localization

Stav: Absolvoval od 2019 do 2020.