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Nový Zbyněk Ph.D.

Journals

DVOŘÁKOVÁ BENDOVÁ, K., V. RACLAVSKÝ, R. NOVOTNY, D. LUPTAKOVA, M. POPPER, Z. NOVÝ, M. HAJDÚCH, M. PETŘÍK
[68Ga]Ga-Ornibactin for Burkholderia cepacia complex Infection Imaging Using Positron Emission Tomography. Journal of Medicinal Chemistry. 2023, ISSN: 0022-2623, PMID: 37252893,
REISSIG, F., K. ZACHSLER, Z. NOVÝ, M. PETŘÍK, K. DVOŘÁKOVÁ BENDOVÁ, D. KURFÜRSTOVÁ, J. BOUCHAL, M. ĹUDIK, F. BRANDT, K. KOPKA, M. KHOYLOU, H. PIETZSCH, M. HAJDÚCH, C. MAMAT
Modulating the pharmacokinetic profile of Actinium-225-labeled macropa-derived radioconjugates by dual targeting of PSMA and albumin. Theranostics. 2022, 12(17), 7203-7215, ISSN: 1838-7640, PMID: 36438496,
BARTA, P., R. KAMARAJ, M. KUCHAROVA, Z. NOVÝ, M. PETŘÍK, K. DVOŘÁKOVÁ BENDOVÁ, M. HAJDÚCH, P. PÁVEK, F. TREJTNAR
Preparation, In Vitro Affinity, and In Vivo Biodistribution of Receptor-Specific 68Ga-Labeled Peptides Targeting Vascular Endothelial Growth Factor Receptors. Bioconjugate Chemistry. 2022, 33(10), 1825-1836, ISSN: 1043-1802, PMID: 36197842,

Books & book chapters

In vivo methods for evaluation of radiolabelled compounds, 1.vyd., Olomouc, Palacky University, 2021, 38, 291-298, Dedication: LO1304, ISBN: 978-80-244-6049-9,
Basic in vitro methods for evaluation of radiolabelled compounds, 1.vyd., Olomouc, Palacky University, 2021, 39, 299-306, Dedication: LO1304, ISBN: 978-80-244-6049-9,

Intellectual property

NANOPARTICLES BASED ON HYDROXYAPATITE AND HYDROPHILIC POLYMER FOR THE USE IN BIOLOGY AND MEDICINE (Hrubý)

Utility Patent: CZ 32279; Granted: 6.11.2018; Ownership: Institute of Macromolecular Chemistry CAS, Palacky University, Olomouc; Inventors: Hrubý Martin, Petřík Miloš, Lobaz Volodymyr, Nový Zbyněk

​Status: Terminated

IODINATED ANOALOGUES OF CHOLINE, METHODS OF PREPARATION THEREOF, AND USE THEREOF AS MEDICAMENTS "Cholines" (Hrubý)
  1. Published Application PV 2016-117 under PV 2016-117 (13.9.2017)
  2. Published Application PCT/CZ2017/050010 under WO 2017/148455 (8. 9. 2017)
  3. Patent: EP 3423441. Granted: 27.10.2021. Ownership: Palacký University Olomouc. Inventors: Švec Pavel, Hrubý Martin, Kučka Jan, Sedláček Ondřej, Petřík Miloš, Nový Zbyněk, Hajdúch Marián

Status: Available

Doctoral mentorship

Hajduová Katarína

Multimodal imaging methods for preclinical testing of novel bioactive molecules

Status: Ongoing from 2023.

Master mentorship

Holá Michaela MSc.

Gallium-68 labelled RGD peptides evaluation for imaging of glioblastoma multiforme

Status: Graduated from 2015 to 2017.
Planičková Barbora

Radiolabeled agents for the diagnosis of prostate cancer

Status: Graduated from 2016 to 2019.
Hajduová Katarína

New PSMA ligands for prostate cancer diagnosis and therapy

Status: Graduated from 2021 to 2023.

Bachelor mentorship

Adámková Hana

Imaging of glioblastoma multiforme in a mouse model using PET/CT system

Status: Graduated from 2014 to 2015.
Floriánová Adéla

Preclinical testing of novel radiolabeled receptor-specific ligands for tumor imaging

Status: Ongoing from 2022.
Flašarová Dominika

Gallium-68 labelled RGD peptides for PET imaging of glioblastoma multiforme

Status: Graduated from 2015 to 2016.

Open positions

Project: Multimodal imaging methods for testing bioactive molecules in vivo
Supervisors: Petřík Miloš Ph.D., Nový Zbyněk Ph.D.
Available: 2
Intended for: Doctoral training
Summary: The student will employ modern in vivo imaging techniques namely positron emission tomography, single-photon emission tomography, computed tomography and optical imaging in order to elucidate effect of novel anticancer or antimicrobial agents. The other part of the project will be assessment of novel radiotracers directed towards targets expressed by tumour cells or by microbial pathogens. Daily work routine will include all proper working steps common in radiopharmacy, i.e. starting with gaining an radioisotope from dedicated source, radiolabelling of selected compound, quality control (HPLC/TLC), stability tests, in vitro testing of biological properties and finally in vivo procedures (biodistribution, static/dynamic imaging). Expected previous education includes medicine, pharmacy, pharmacology or related field.
Project: Multimodal imaging methods for preclinical testing of new bioactive molecules
Supervisors: Nový Zbyněk Ph.D., Petřík Miloš Ph.D.
Available: 2
Intended for: Doctoral training
Project: Small animal imaging using microPET/SPECT/CT system in preclinical developement of potential drugs
Supervisors: Nový Zbyněk Ph.D.
Available: 1
Intended for: Bachelor training