Nový Zbyněk Ph.D.
Journals
[68Ga]Ga-Ornibactin for Burkholderia cepacia complex Infection Imaging Using Positron Emission Tomography.
Journal of Medicinal Chemistry.
2023,
ISSN: 0022-2623,
PMID: 37252893,
Modulating the pharmacokinetic profile of Actinium-225-labeled macropa-derived radioconjugates by dual targeting of PSMA and albumin.
Theranostics.
2022,
12(17),
7203-7215,
ISSN: 1838-7640,
PMID: 36438496,
Preparation, In Vitro Affinity, and In Vivo Biodistribution of Receptor-Specific 68Ga-Labeled Peptides Targeting Vascular Endothelial Growth Factor Receptors.
Bioconjugate Chemistry.
2022,
33(10),
1825-1836,
ISSN: 1043-1802,
PMID: 36197842,
Books & book chapters
In vivo methods for evaluation of radiolabelled compounds,
1.vyd.,
Olomouc,
Palacky University,
2021,
38,
291-298,
Dedication: LO1304,
ISBN: 978-80-244-6049-9,
Basic in vitro methods for evaluation of radiolabelled compounds,
1.vyd.,
Olomouc,
Palacky University,
2021,
39,
299-306,
Dedication: LO1304,
ISBN: 978-80-244-6049-9,
Intellectual property
NANOPARTICLES BASED ON HYDROXYAPATITE AND HYDROPHILIC POLYMER FOR THE USE IN BIOLOGY AND MEDICINE (Hrubý)
Utility Patent: CZ 32279; Granted: 6.11.2018; Ownership: Institute of Macromolecular Chemistry CAS, Palacky University, Olomouc; Inventors: Hrubý Martin, Petřík Miloš, Lobaz Volodymyr, Nový Zbyněk
Status: Terminated
IODINATED ANOALOGUES OF CHOLINE, METHODS OF PREPARATION THEREOF, AND USE THEREOF AS MEDICAMENTS "Cholines" (Hrubý)
- Published Application PV 2016-117 under PV 2016-117 (13.9.2017)
- Published Application PCT/CZ2017/050010 under WO 2017/148455 (8. 9. 2017)
- Patent: EP 3423441. Granted: 27.10.2021. Ownership: Palacký University Olomouc. Inventors: Švec Pavel, Hrubý Martin, Kučka Jan, Sedláček Ondřej, Petřík Miloš, Nový Zbyněk, Hajdúch Marián
Status: Available
Doctoral mentorship
Hajduová Katarína
Multimodal imaging methods for preclinical testing of novel bioactive molecules
Status:
Ongoing from 2023.
Master mentorship
Holá Michaela MSc.
Gallium-68 labelled RGD peptides evaluation for imaging of glioblastoma multiforme
Status:
Graduated from 2015 to 2017.
Planičková Barbora
Radiolabeled agents for the diagnosis of prostate cancer
Status:
Graduated from 2016 to 2019.
Hajduová Katarína
New PSMA ligands for prostate cancer diagnosis and therapy
Status:
Graduated from 2021 to 2023.
Bachelor mentorship
Adámková Hana
Imaging of glioblastoma multiforme in a mouse model using PET/CT system
Status:
Graduated from 2014 to 2015.
Floriánová Adéla
Preclinical testing of novel radiolabeled receptor-specific ligands for tumor imaging
Status:
Ongoing from 2022.
Open positions
Project: | Multimodal imaging methods for testing bioactive molecules in vivo |
---|---|
Supervisors: | Petřík Miloš Ph.D., Nový Zbyněk Ph.D. |
Available: | 2 |
Intended for: | Doctoral training |
Summary: | The student will employ modern in vivo imaging techniques namely positron emission tomography, single-photon emission tomography, computed tomography and optical imaging in order to elucidate effect of novel anticancer or antimicrobial agents. The other part of the project will be assessment of novel radiotracers directed towards targets expressed by tumour cells or by microbial pathogens. Daily work routine will include all proper working steps common in radiopharmacy, i.e. starting with gaining an radioisotope from dedicated source, radiolabelling of selected compound, quality control (HPLC/TLC), stability tests, in vitro testing of biological properties and finally in vivo procedures (biodistribution, static/dynamic imaging). Expected previous education includes medicine, pharmacy, pharmacology or related field. |
Project: | Multimodal imaging methods for preclinical testing of new bioactive molecules |
---|---|
Supervisors: | Nový Zbyněk Ph.D., Petřík Miloš Ph.D. |
Available: | 2 |
Intended for: | Doctoral training |
Project: | Small animal imaging using microPET/SPECT/CT system in preclinical developement of potential drugs |
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Supervisors: | Nový Zbyněk Ph.D. |
Available: | 1 |
Intended for: | Bachelor training |